Are your symptoms non-Hodgkin lymphoma?

The Early Warning Signs and Symptoms of Non-Hodgkin Lymphoma

Non-Hodgkin lymphoma is a cancer of the immune system that has been linked to chemicals in commonly used products. It is easy to overlook non-Hodgkin lymphoma symptoms because they seem, at first, like no big deal. Understanding your risks and what to look for is important. The earlier you get treatment, the better the outcome.

Written by: Lisa Merriam | Medical review by: Samuel Sarmiento, MD, MPH, MBA | Legal review by: Sean Duddy, JD |

Updated on:Jul 22, 2025

Key non-Hodgkin lymphoma information

  1. 80,350 people are diagnosed with non-Hodgkin lymphoma every year. Your chances of getting it are 1 in 44 if you are a man and 1 in 54 if you are a woman.

  2. Non-Hodgkin lymphoma is a life-threatening disease. That’s why it is important to know the early-stage lymphoma symptoms. If you discover you have it early, in stage 1, your chance of surviving five years is 87.7%.

  3. Non-Hodgkin lymphoma symptoms feel like a cold or the flu, but they last longer and get worse over time. Fever, coughing, night sweats, swollen glands and feeling very tired are some non-Hodgkin lymphoma signs and symptoms to take seriously.

  4. The older you are, the higher your risk of getting non-Hodgkin lymphoma. More than half of patients with it get diagnosed when they are over 65 years old.

  5. A common cause of non-Hodgkin lymphoma is genetic mutations of white blood cells called lymphocytes. Exposure to chemicals like pesticides is linked to causing some of these mutations.

Find out if your non-Hodgkin lymphoma was caused by exposure to Roundup

β€œStudies have linked non-Hodgkin lymphoma to long-term exposure to glyphosate, the active ingredient in Roundup weed killer. People who used Roundup regularlyβ€”especially agricultural workers, landscapers, and home gardenersβ€”may be at higher risk. If you’ve been diagnosed with non-Hodgkin lymphoma, you may be eligible to file a lawsuit and seek compensation. Click below to see if you qualify to file a claim.”

Learn more about the connection between non-Hodgkin lymphoma and Roundup exposure:

β€” Sean Duddy, JD, Partner at Duddy Czarnecki

What is non-Hodgkin lymphoma?

Lymphoma is a kind of cancer that’s classified into two main categories: Hodgkin and non-Hodgkin. Non-Hodgkin lymphoma is the more common type, accounting for approximately 90% of all lymphoma cases. It affects the part of your body that fights infection, called your lymphatic system. This system creates a type of white blood cell called a lymphocyte that finds and attacks viruses and bacteria to keep you healthy. Think of it as a home security system that keeps these disease-causing intruders out.

When you get non-Hodgkin lymphoma, your lymphatic system goes haywire. It creates abnormal lymphocytes that multiply out of control and start attacking healthy tissue. It’s as if your home security system stops fighting intruders and starts attacking your house. 

Your lymph system is spread out all over your body, like having home security detectors in different rooms around your house. That means non-Hodgkin lymphoma can start nearly anywhere, but it typically starts in the lymph nodes in your neck, chest, armpits and groin. It can also show up in your spleen, liver and thymus.

Types of non-Hodgkin lymphoma linked to Roundup exposure

The two main types of non-Hodgkin lymphoma are B-cell lymphomas and T-cell/NK-cell lymphomas. However, there are more than 70 subtypes that have been discovered. Some of the most common subtypes of non-Hodgkin lymphoma have been associated with Roundup exposure, including the following:

  • Diffuse large B-cell lymphoma (DLBCL) is a fast-growing type of non-Hodgkin lymphoma that starts in white blood cells called B cells and often causes swollen lymph nodes, fever and weight loss.

  • Chronic lymphocytic leukemia (CLL) is a slow-growing cancer of the blood and bone marrow that affects a type of white blood cell and can cause fatigue, swollen glands and infections.

  • Follicular lymphoma (FL) is a slow-growing cancer that starts in B cells and usually causes painless swelling in the lymph nodes.

Non-Hodgkin lymphoma in the body.

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Early warning signs of non-Hodgkin lymphoma

Non-Hodgkin lymphoma signs and symptoms are easy to miss. You might think you have a lingering cold, bad flu or that you’re just tired or run down.

Don’t dismiss early-stage symptoms. It’s better to ask and find out you have nothing to worry about than to ignore them.

What are the non-Hodgkin lymphoma symptoms to look out for? Swelling of glands in your neck, groin or underarm is the most common early sign. If you have fevers, a cough, night sweats, rashes or dry skin that won’t go away, take them seriously. You might lose weight without trying or feel tired all the time.

Discovering non-Hodgkin lymphoma early gives you more treatment options and can help lead to a better outcome. That’s why it’s important to see a doctor right away if you have any of these symptoms.

Non-Hodgkin lymphoma early symptoms.

What are the most common non-Hodgkin lymphoma symptoms?

Non-Hodgkin lymphoma presents many of the same symptoms as other diseases that are less serious. If you have some of these symptoms, it doesn’t necessarily mean that you have non-Hodgkin lymphoma. However, if your symptoms won’t go away or get worse over time, it’s worth talking to your healthcare provider.

Every person’s case is different, but here are some common non-Hodgkin lymphoma symptoms:

  • Swelling in your neck, armpits, belly or groin that doesn’t hurt

  • A general feeling of fatigue that no amount of rest helps

  • Dry, itchy skin or a red rash

  • Nausea, vomiting or abdominal pain

  • A feeling of fullness in your belly, possibly caused by swollen lymph nodes in the area

  • Coughing or shortness of breath, often with a feeling of heaviness in your chest

  • Headaches, confusion or problems concentrating

  • Feeling weak in your arms or legs

  • Unusual bleeding or bruising easily

  • Bone pain or ache in the center of your bones

If your case is more advanced or you have a fast-growing form of non-Hodgkin lymphoma, you might experience β€œB symptoms.” It’s very important to see a healthcare provider if you have any or all of these:

  • Heavy night sweats

  • A high fever that won’t go away

  • Loss of appetite

  • Weight loss you can’t explain

The most common symptoms of non-Hodgkin lymphoma.

Symptoms of non-Hodgkin lymphoma in the chest

The signs that non-Hodgkin lymphoma is in your chest include:

  • Pain or pressure in your chest

  • Shortness of breath or difficulty catching your breath

  • A cough that doesn’t go away

  • Having a hard time swallowing

  • Swelling in your neck or face

Signs of non-Hodgkin lymphoma in the stomach

If you get non-Hodgkin lymphoma in your belly area, such as your stomach, intestines, spleen, liver or surrounding lymph nodes, you may notice:

  • Pain or cramping in your belly

  • Feeling full or bloated

  • Swollen belly area

  • Not feeling hungry and not wanting to eat

  • Losing weight without trying

  • Nausea and possibly throwing up

  • Constipation or diarrhea

Symptoms of non-Hodgkin lymphoma in the brain

Non-Hodgkin lymphoma can be in your brain or spine, leading to symptoms like:

  • Headaches, especially in the morning

  • Seizures

  • Difficulty remembering things or confusion

  • Changes in how you see

  • Numb or weak arms or legs

  • Having a hard time speaking

  • Difficulty walking

  • Changes in your personality or behavior

Non-Hodgkin lymphoma symptoms by gender and age

Swollen glands are common in all non-Hodgkin lymphoma cases. Some of the other symptoms can be different, depending on your age and gender.

Children and teens often get more aggressive lymphomas, so they more commonly have β€œB symptoms.” These include fevers, night sweats and unexplained weight loss. Older adults often get slow-growing lymphomas, so they may get symptoms that are mistaken for a cold or simply aging. They might not even notice the disease. Women can get lymphomas that are affected by monthly changes in hormone levels.

Here are the different non-Hodgkin lymphoma symptoms to watch out for in men, women and kids:

Symptoms of non-Hodgkin lymphoma in women

Symptoms of non-Hodgkin lymphoma in women.

Non-Hodgkin lymphoma can attack a woman’s reproductive organs. These signs are easy to mistake for something else. See a doctor right away if you experience:

  • Pain or pressure in your pelvis

  • Unusual bleeding during your period, between cycles, or after you’ve gone through menopause

  • Pain during sex

Symptoms of non-Hodgkin lymphoma in men

Symptoms of non-Hodgkin lymphoma in men.

Men are most likely to experience common non-Hodgkin lymphoma symptoms such as:

  • Painless swelling in your neck, armpit or groin

  • Always feeling tired

  • Fevers and night sweats

  • Unexplained weight loss

  • Chest pressure or pain

  • Cough or feeling short of breath

  • Swelling in the belly area

Symptoms of non-Hodgkin lymphoma in kids

Symptoms of non-Hodgkin lymphoma in children.

The signs of non-Hodgkin lymphoma in children may be associated with the cold or flu. Be on the lookout for:

  • Swollen lymph nodes

  • Coughing or difficulty breathing

  • Feeling full even if they eat only a small amount of food

  • Unexplained weight loss

  • Stomach pain or vomiting

  • Fever

  • Night sweats

  • Feeling tired all the time

Who does non-Hodgkin lymphoma affect?

What causes non-Hodgkin lymphoma?

How do you get non-Hodgkin lymphoma? When you understand who is at risk, you can watch out for symptoms you might otherwise ignore. Pinpointing what causes non-Hodgkin lymphoma isn’t easy. Several risk factors include:

  • Age: While you can get non-Hodgkin lymphoma at any age, people over age 60 are most likely to get this kind of cancer.

  • Age: While you can get non-Hodgkin lymphoma at any age, people over age 60 are most likely to get this kind of cancer.

  • Gender: Men have a slightly higher risk of getting non-Hodgkin lymphoma than women.

  • Family history: You can inherit genes from a close family member that increase your risk of getting non-Hodgkin lymphoma.

  • Exposure to certain chemicals: Dangerous chemicals in pesticides may be linked to a higher risk of non-Hodgkin lymphoma.

  • Radiation exposure: Survivors of a nuclear bomb or nuclear reactor accident can be exposed to radiation that increases non-Hodgkin lymphoma risks. If you get radiation treatment for a different kind of cancer, you might also face a higher risk.

  • Infections: The Epstein-Barr virus and certain bacteria can put you at risk of developing non-Hodgkin lymphoma.

  • Weak immune system: If you have a disease like HIV/AIDS or take drugs after an organ transplant, you may be at risk of getting certain kinds of non-Hodgkin lymphoma.

Could exposure to Roundup be linked to your non-Hodgkin lymphoma?

β€œResearch has found a possible link between long-term exposure to glyphosate, the main ingredient in Roundup, and an increased risk of developing non-Hodgkin lymphoma. Many patients may not realize that past exposure to Roundup at work or at home could have contributed to their diagnosis. If you or a loved one has been affected, you may be able to take legal action and seek compensation.”

Learn more about the connection between non-Hodgkin lymphoma and commonly used products like Roundup:

β€” Samuel Sarmiento, MD, MPH, MBA, CEO at Juniper Life Sciences

How do you get non-Hodgkin lymphoma?

Who is most likely to get non-Hodgkin lymphoma?

Getting exposed to dangerous chemicals, harmful substances and radiation increases your risk of getting non-Hodgkin lymphoma. If you work in any of the following industries or settings, you should be on the lookout for symptoms:

  • Farmers and agricultural workers: You may be exposed to harmful chemicals in pesticides and herbicides. Planting, treating, harvesting and processing crops puts you in direct contact with these substances.

  • Textile workers: If you work with natural and synthetic textiles and fabrics, as well as with leather, you have over twice the risk of getting non-Hodgkin lymphoma.

  • Painters and construction workers: You may be exposed to asbestos, dust and chemical fumes that can increase your cancer risk.

  • Hairdressers and beauticians: If you work in this field, you come into close contact with hair dyes, chemical straighteners and cosmetic ingredients linked to higher cancer risks.

  • Healthcare workers: Health professionals can be exposed to high levels of radiation in administering cancer therapies and in imaging, which can lead to higher cancer rates.

  • Factory workers: Working in factories that make products containing dangerous chemicals or that use solvents and dyes to produce products may increase your non-Hodgkin lymphoma risk.

How is non-Hodgkin lymphoma treated?

You have several choices of treatments for non-Hodgkin lymphoma. These include radiation, targeted therapy, immunotherapy and, more recently, stem cell transplants.

The therapy that’s right for you depends on what type of non-Hodgkin lymphoma you have, its stage of development and where it is in your body. Your age and overall health also matter. Unfortunately, some promising therapies are not yet covered by insurance. This means that your ability to pay for them can also be a factor.

FAQs

  • Is non-Hodgkin lymphoma genetic?

    Non-Hodgkin lymphoma isn’t considered to be a genetic disease or one that runs in families. More often, lymphoma forms through genetic mutations or changes in cells that cause them to grow in ways that aren’t normal. It’s believed that exposure to certain chemicals and radiation can cause some of these mutations.

  • Where does non-Hodgkin lymphoma usually start?

    Non-Hodgkin lymphoma is a cancer of the lymph system that often starts in your lymph nodes. These are small glands located in your neck, chest, belly and pelvis. Your lymph nodes and lymph system play an important part in protecting you from viruses and bacteria.

    Other common places where non-Hodgkin lymphoma starts are other parts of your immune system. This includes your spleen, bone marrow, thymus, adenoids and tonsils. In some cases, it can start in parts of your digestive system, like your stomach, intestines and liver.

  • How long can non-Hodgkin lymphoma go undetected?

    Depending on the type you have, non-Hodgkin lymphoma can go unnoticed for several years. Some forms of non-Hodgkin lymphoma are aggressive, meaning they grow very quickly. You might notice symptoms sooner and get diagnosed earlier. Other types of low-grade non-Hodgkin lymphoma grow slowly over years. You might have no symptoms or such mild symptoms that you might not realize anything is wrong.

    These low-grade types of non-Hodgkin lymphoma are often not found until they are very advanced. They can grow slowly over 5–10 years and then suddenly start growing very quickly. That’s why it’s so important to take even mild symptoms seriously, especially if you have risk factors.

Meet the experts behind the article

Lisa Merriam
Lisa Merriam

Written by:

Lisa Merriam

Lisa Merriam is an experienced copywriter specializing in medical content, combining technical precision with clarity to ensure articles are accessible and accurate.

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Samuel Sarmiento, MD, MPH, MBA
Dr. Samuel Sarmiento

Medical review by:

Samuel Sarmiento, MD, MPH, MBA

Dr. Sarmiento is a physician, consultant, and entrepreneur with a diverse background in surgery, public health, and business. His experience includes solving complex problems in healthcare and beyond, with a strong focus on personalized, preventive medicine.

Read more
Sean Duddy, JD
Sean Duddy

Legal review by:

Sean Duddy, JD

Sean Duddy is a seasoned attorney with a strong background in technology and litigation. He specializes in mass torts and class action cases. He is recognized for his innovative approach to legal challenges, having developed platforms to manage large-scale arbitrations and secure substantial settlements.

Read more